AIM:To evaluate the clinical effects of fasudil therapy on nonarteritic anterior ischemic optic neuropathy(NAION).

METHODS:Seventy eyes of 70 patients with NAION in our hospital were collected and randomly divided into treatment group(35 patients)which was intravenously injected fasudil, and control group(35 patients)which was intravenously injected composite salvia miltiorrhiza injection. At the 4wk of follow-up, the best corrected visual acuity(BCVA)and visual field were observed and compared.

RESULTS: The total effective rate of BCVA in treatment group was 86%, in control group was 57%. The difference in two groups had statistical significance(P<0.05). The improvement rate of visual field in treatment group was 83% and in control group was 57%. The difference in two groups had statistical significance(P<0.05)

CONCLUSION:The clinical effects of fasudil on NAION are better than conventional medication.