Retinopathy of prematurity(ROP)is a vasoproliferative retinopathy with unmatured and low weight infants. Now in domestic, the main treatment methods are cryotherapy and laser coagulation, there are some medication treatment researches and fundamental researches that have been reported in recent years. This review describes the application of bevacizumab, ranibizumab and other research-based drugs in new progress of the treatment study for ROP.