AIM: To observe retinal hemodynamic influence of compound xueshuantong capsule on nonproliferative diabetic retinopathy(NPDR)after laser photocoagulation.

METHODS: A total of 41 patients(72 eyes)with NPDR after laser photocoagulation were enrolled in this study. They were all given compound xueshuantong capsule, and used color Doppler flow imaging for detection of retinal hemodynamics.

RESULTS: After treatment, patients with retinal blood perfusion significantly improved; central retinal arterial peak systolic velocity(PSV), end-diastolic velocity(EDV)and medial velocity(Vm)were increased, while the resistance index(RI)decreased. The difference have statistical significance(P<0.05). The visual acuity of 61 eyes improved, efficiency was 85%. Visual acuity was related with PSV, Vm and RI.

CONCLUSION: Compound xueshuantong capsule can improve retinal blood perfusion for nonproliferative diabetic retinopathy after laser photocoagulation, which is related to improvement of visual prognosis.