AIM:To evaluate the efficacy of a variety of lacrimal duct obstruction diseases treated by Nd: YAG laser lacrimal duct forming surgery using Meta analysis.

METHODS: Relevant database in 1995-2012 and other network resources were retrieved by computer and manual, using MetaAnalyst software on the Meta analysis. Analysis of indicators: disease prevalence between men and women, the prevalence of various lacrimal duct diseases and the effective rate of Nd: YAG laser lacrimal duct forming surgery to treat a variety of lacrimal duct obstruction diseases.

RESULTS: According to the inclusion and exclusion criteria, 38 subjects were selected, the cumulative number of patients included 4 638 cases, the men combined prevalence was 23%; the women combined prevalence was 77%; lacrimal punctum occlusion combined prevalence was 6.0%, combined treatment efficiency was 88.1%; lacrimal canaliculus obstruction combined prevalence of 17.9%, combined efficiency was 85.6%; lacrimal common canaliculus obstruction combined prevalence was 14.0%, 92.7% of the combined effective rate; nasolacrimal duct obstruction combined prevalence of was 43.6%, 93.3% of the combined effective rate; chronic dacryocystitis combined prevalence was 18.4%, 76.6% of the combined efficiency. All study has heterogeneity. Selection of random effects model combined effect size. Model was statistically significant(P<0.001).

CONCLUSION: The prevalence of lacrimal duct obstruction diseases of women are higher than men, lacrimal canaliculus obstruction in the lacrimal duct obstruction is in the lowest prevalence, nasolacrimal duct obstruction is the main type of lacrimal duct obstruction disease, Nd: YAG laser lacrimal forming surgery has slightly efficacy different in various lacrimal duct obstruction diseases.