AIM: To evaluate the treatment process of toxic anterior segment syndrome(TASS)and to found out the effective treatment, aetiological agent and prognosis.

METHODS: A total of 6 cases(7 eyes)were suspected with TASS by clinical situations. Bacterial infectious endophthalmitis could be ruled out by anterior chamber and vitreous body paracentesis. All patients were treated with local application of antibiotics and glucocorticoid eyedrops, and some patients were treated with intravitreal injection of 1mg vancomycin and 2mg ceftazidime. The therapeutic effects after treatment were observed.

RESULTS: There were no bacterial growth in 6 cases(7 eyes)with TASS by anterior chamber fluid and vitreous humor culture. After administrated with antibiotics and glucocorticoid eye drops, inflammation was steady in 1 case(2 eyes). After anterior chamber irrigation and intravitreal medicine injection, anterior chamber inflammation were improved significantly in 5 cases(5 eyes). No ocular abnormality was seen in following up 6mo. Risk factors was considered as the cause of sterilization pot, the incidence decreased obviously by timely cleaning change and filter.

CONCLUSION: TASS is a rare complication of ocular anterior segment surgery. Good prognostic results will be achieved with correct analysis, criterion and effective treatment.