AIM: To investigate the distribution and drug resistance of the pathogenic bacteria in acute bacterial conjunctivitis in Xingtai, and to provide a reliable basis for clinical diagnosis and treatment.

METHODS: Secretion specimens were taken from the patients with acute bacterial conjunctivitis in Xingtai Ophthalmic Hospital during January 2010 to December 2012 for bacterial culture. The pathogenic bacteria and drug sensitivity test were analyzed.

RESULTS: Of the 186 specimens, 150(80.6%)were positive in culture, in which 127(84.7%)were gram-positive bacteria, the first three species were Staphylococcus epidermidis(42/127, 33.1%), Human staphylococal(15/127, 11.8%), Staphylococcus haemolyticus(6/127, 4.7%). Twenty-three(15.3%)were gram-negative bacteria, the first four species were Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Enterobacter cloacae, the percentage of all resistance were 13.0%. Gram-positive strains were 100% sensitive to vancomycin, and were resistance to other antibiotics with different degree. Gram negative bacteria had the highest rate of drug resistance to cefoperazone 87.0%).

CONCLUSION:Some opportunistic bacteria including Staphylococcus epidermidis have become the majority of pathogenic bacteria of acute bacterial conjunctivitis in this area. Both gram-positive bacteria and gram-negative bacteria were higher to drug resistance. Early bacterial culture combined with drug sensitivity test is grate significance for clinical diagnosis and reasonable clinical chose of antibiotics.