AIM:To explore the effect of Danshen injection iontophoresis combined with lumbrukinase on early patients with retinal vein occlusion(RVO), and observe the prognosis to provide objective basis for clinical

METHODS: Eighty-two patients(117 eyes)with early RVO were randomly selected in our hospital from January, 2011 to April, 2014, 41 cases(59 eyes)of control group treated with Lumbrokinase. Forty-one cases(58 eyes)of the observation group, treated with Danshen injection iontophoresis combined with lumbrokinase. The main indexes were the treatment effect, visual acuity and retinal circulation time.

RESULTS: The total effective rate of the observation group was 85.4%(35/41), more than that of control group 68.3%(28/41), the difference was statistically significant(P<0.05).The invalid rate of the observation group was 14.6%(6/41), lower than that of the control group 31.7%(13/41), the difference was statistically significant(P<0.05). The vision of the observation group 4.8～5.0 was 53.7%(22/41), more than that of control group 41.5%(17/41), the difference was statistically significant(P<0.05). The restore vision of the observation group 4.3～4.7 was 31.7%(13/41), lower than that of the control group 41.5%(17/41), the difference was statistically significant(P<0.05). After treatment, retinal circulation time of two groups were lower than before treatment, the difference was statistically significant(P<0.05). After treatment of retinal vein circulation time of the observation group was 8.15±1.30s, 9.70±1.28s lower than that of the control group, the difference was statistically significant(P<0.05).

CONCLUSION: There is better effective on Danshen injection iontophoresis combined with Lumbrokinase for early retinal vein occlusion, and can improve the patient's visual acuity, promote the rehabilitation of patients.