方法：入选我院2013-01/2014-01先天性白内障患儿70例110眼，按患者年龄分为A组(<2岁)、B组(2～6岁)、C组(7～12岁)，均进行先天性白内障摘除联合IOL植入术，比较三组术后角膜曲率、眼轴、屈光状态情况，分析其眼轴变化影响因素。

结果：A组、B组、C组术后角膜曲率差异无统计学意义(P>0.05)； A组术后与术后3mo角膜曲率比较差异均有统计学意义(P<0.05)，B和C组术后与术后3mo角膜曲率差异无统计学意义(P>0.05)； A组术后3mo角膜曲率差异显著高于B组和C组(P<0.05)，B组和C组术后3mo角膜曲率差异无统计学意义(P>0.05)； A组、B组和C组术后眼轴长度差异无统计学意义(P>0.05)； A组术后与术后3mo眼轴长度比较差异均有统计学意义(P<0.05)，B和C组术后与术后3mo眼轴长度差异无统计学意义(P>0.05)； A组术后3mo眼轴长度差异显著高于B组和C组(P<0.05)，B组和C组术后3mo眼轴长度差异无统计学意义(P>0.05)； 三组患者术后屈光状态呈现近视移动变化趋势，A组术后屈光变化率及屈光度变化显著高于B和C组，差异有统计学意义(P<0.05)。

结论：先天性白内障摘除联合IOL植入术后屈光状态呈现近视化趋势，2岁以下患儿表现显著。近视化影响因素主要为眼轴增长。

METHODS: Seventy cases(110 eyes)with congenital cataract from January 2013 to January 2014 in our hospital were selected, according to the age of patients, they were divided into group A(<2 years old), group B(2～6 years old), group C(7～12 years old). They were all given cataract extraction combined with IOL implantation in congenital cataract. Corneal curvature, axial length, refractive status of three groups after operation were compared, the influence factors ocular axis changes were analyzed.

RESULTS: There were no statistically significant differences in corneal curvature of groups A, B, and C after operation(P>0.05); The differences had statistical significances of the corneal curvature of group A after surgery and 3mo after operation(P<0.05), there were no significant differences of the corneal curvature of group B, group C after surgery and 3mo after operation(P>0.05); the corneal curvature 3mo after operation of group A was significantly higher than that of groups B and C(P<0.05), there were no significant differences in the corneal curvature between group B, and group C after 3mo(P>0.05); There were no statistical significances on axial length after operation in groups A, B, and C(P>0.05); Ocular axial length difference of group A 3mo after surgery was significantly higher than that of groups B and C(P<0.05), ocular axial length had no statistical difference of group B, group c 3mo after surgery(P>0.05). Refractive status of three groups after operation showed myopia moving trend, refractive change rate and refractive diopter of group A after operation was significantly higher than that of group B, group C, the difference was statistically significant(P<0.05).

CONCLUSION: After congenital cataract extraction combined with IOL implantation, patients present myopia refractive state trend. Performance of children below 2 years old is significant. The main factor of myopia is axial growth.