AIM: To explore the relationship between different timing of vitreous surgery and prognosis after the open globe injuries.

METHODS: Fifty-eight cases(58 eyes)with open globe injuries were chosen in our hospital from June 2011 to June 2013, and randomly divided into observation group and control group to have vitreous surgery in early phase and normal time respectively. Thirty cases(30 eyes)in the observation group were received vitreous surgery during 3d, and 28 cases(28 eyes)in the control group from one to two weeks. The vitreous surgery of two groups of patients were finished by the author herself. The ocular injury before surgery, the effect of surgery treatment and the incidence of complications after surgery of the two groups of patients were compared.

RESULTS: The eye damage situation such as lens rupture,vitreous hemorrhage, retinal detachment and corneal laceration of two groups of patients before surgery were no significant statistical difference(P>0.05). The postoperative therapeutic effect of observation group was better than the control group(χ²=6.869, P<0.05); the postoperative complications of observation group was obviously lower than the control group(P<0.05).

CONCLUSION: The timing of vitreous surgery of patients with open globe injuries correlate with the prognosis, which prompts that better therapeutic effect can be achieved and the occurrence of complications can be reduced in early vitreous surgery of the patients with open globe injuries.