AIM: To evaluate the clinical efficacy of posterior continuous curvilinear capsulorhexis(PCCC)combined with anterior vitrectomy in preventing posterior capsule opacification of congenital cataract surgery.

METHODS: Postoperative clinical follow-up data of 82 cases(87 eyes)with congenital cataract treated in Eye Center of our hospital from January 2011 to August 2014 were retrospectively analyzed. The patients were divided into the surgical control group(38 cases, 40 eyes, recieved phacoemulsification + PCCC)and the study group(44 cases, 47 eyes, accepted phacoemulsification + PCCC + anterior vitrectomy). The incidence of central optic axis opaque and postoperative visual acuity distribution were recorded at 1a follow-up. Intraoperative and postoperative complications were observed.

RESULTS: The rate of central optic axis opaque grade 0 in control group was 37.5%, compared to 76.6% in study groups. The opacity distribution ratio of grade 1,2,3 and 4 in study group were lower than that of control group, and the central optic axis opacity distribution ratio in study group was significantly better than that of control group(P<0.05). The 19 eyes(47.5%)of visual acuity testing ≤0.5 in control group, was higher than the 7 eyes(14.89%)of that in the study group, The 21 eyes(52.5%)of visual acuity testing >0.5 in control group was lower than the 40 eyes(85.11%)of that in study group. The visual acuity between two groups has statistical significance difference after 1a follow-up(P<0.05), and the visual acuity in study group was significantly better than that in the control group. The postoperative intraocular pressure at 1mo and 1a follow-up was lower than before operation in two groups(P<0.05), but there was no significant difference between two groups in intraocular pressure(P<0.05).

CONCLUSION: Combination of phacoemulsification, PCCC and anterior vitrectomy presents reliable clinical effects on postoperative central optic axis opacity distribution ratio and visual acuity, and it should be adopted to prevent the occurrence of posterior capsule opacification.