AIM:To observe clinical effects of endoscopic dacryocystorhinostomy combined with adjunctive mitomycin C(MMC)on the treatment of recurrent chronic dacryocystitis after lacrimal duct intubation.

METHODS:Sixty-two eyes of 62 cases with recurrent chronic dacryocystitis after lacrimal duct intubation were randomly divided into two groups: treatment group(31 cases)and control group(31 cases). Patients in the treatment group were undergone endoscopic dacrystorhinostomy combined with MMC placed on the anastomotic bone hole.Patients in the control group only received endoscopic dacryocystorhinostomy. The follow-up period arranged from 3 to 12mo.

RESULTS: At 6mo postoperative, the cure rate and effective rate of the treatment group was 90% and 97% respectively, and those of the control group were 74% and 94% respectively. The effective rate of the treatment group was higher than that of the control group significantly(Z=14.66,P<0.05).

CONCLUSION: Endoscopic dacryocystorhinostomy combined with MMC is an effective supplemental method which can prevent postoperative anastomotic cicatricial adhesion and improve the long-term outcome.