Abstract:AIM:To investigate the safety and effectiveness of 25G micro-incision vitrectomy on vitreous hemorrhage.
METHODS:A retrospective review of 200 patients(208 eyes)who were diagnosed as vitreous hemorrhage through the best-corrected visual acuity(BCVA),intraocular pressure(IOP),examination of slit lamp, examination of the ocular fundus and B-mode ultrasongography from January 2012 to June 2014 was taken. All patients were treated by 25G micro-incision vitrectomy. At 1wk,1,3 and 6 mo after the surgeries, the BCVA was retrospectively observed. The changes of IOP, inflammatory reaction and the ocular fundus were observed.
RESULTS: The BCVA was light perception in 16 eyes, hand moving in 82 eyes,finger counting in 49 eyes, 0.01~0.09 in 38 eyes,0.1~0.2 in 23 eyes pre-operatively. At 6mo after operations,the BCVA were hand moving in 1 eyes, finger counting in 2 eyes,0.01~0.09 in 31 eyes, 0.1~0.2 in 29 eyes,>0.2 in 145 eyes. The BCVA of all patients kept stable or increased after operations and the difference before and after the operation was statistically significant(Z=-4.128, P=0.000). The pre-operative mean IOP was 15.29±3.62mmHg. The mean IOP was 13.67±4.93mmHg at 6mo after operations. There were 96 eyes(46.2%)due to diabetic retinopathy,37 eyes(17.8%)due to branch retinal vein obstruction,9 eyes(4.3%)due to central retinal vein obstruction,13 eyes(6.25%)due to retinal periphlebitis,13 eyes(6.25%)due to polypoidal choroidal vasculopathy(PCV),5 eyes(2.4%)due to large retinal aneurys,19 eyes(9.1%)due to retinal hole,16 eyes(7.7%)due to Terson syndrome. Phacoemulcification was performed for 23 eyes(11.1%)during operations. There were 145 eyes(69.7%)with perfusion fluid,21 eyes(10.1%)with C3F8 gas tamponade,17 eyes(8.2%)with air tamponade,25 eyes(12.0%)with silicone oil tamponade. There were 12 eyes(5.8%)with transient hypotony, 8 eyes(3.8%)with increased IOP, 19 eyes(9.1%)with inflammation in anterior chamber, and 10 eyes(4.8%)with vitreous hemorrhage after the surgery. There were no ocular or systemic adverse events observed in other patients.
CONCLUSION: The 25G micro-incision vitrectomy is an effective and safe treatment for the patients with vitreous hemorrhage because of small injury, short operation time, quick recovery.