AIM:To analyze the impact of anxiety on the symptoms of dry eye and inflammation factors in diabetic patients after cataract surgery.

METHODS:Sixty-three diabetic patients(79 eyes)with cataract treated from January 2011 to October 2015 in our hospital were selected. All the patients were conformed to the WHO diagnosis standards of diabetes and cataract. The patients received the phacoemulsification and intraocular lens implantation. After 1d of treatment, Hamilton Anxiety Rating Scale(HAMA)was applied to evaluate the psychological state. According to the evaluation results, the patients were divided into non-anxiety group(<14 scores)and anxiety group(≥14 scores). The non-anxiety group had 34 cases and the anxiety group had 29 cases. The dry eye and inflammatory response of the two groups was compared.

RESULTS:At 1d and 3mo after treatment, the evaluation scores of dry eye of two groups were not significantly different(P>0.05); at 7d after treatment, the dry eye of anxiety group was more serious than that of non-anxiety group(P<0.05). At 1d and 3mo after treatment, the anterior chamber inflammation responses of two groups were not significantly different(P>0.05); at 7d after treatment, the inflammation response of anxiety group was more serious than that of non-anxiety group(P<0.05). At 1d and 3mo after treatment, the levels of IL-1β, IL-6 and TNF-α of the two groups were not significantly different(P>0.05); at 7d after treatment, the levels of IL-1β, IL-6 and TNF-α of anxiety group were significantly higher than those of non-anxiety group(P<0.05).

CONCLUSION: Anxiety has an obvious effect on the dry eye and inflammation response in diabetic patients after cataract surgery. Before surgery, the evaluation of anxiety and the targeted mental intervention is of great importance on the postoperative recovery.