AIM:To discuss and study the effect of trabeculectomy combined with compound Xueshuantong capsules on visual function damage in patients with acute angle-closure glaucoma.

METHODS:One hundred patients(120 eyes)with acute angle-closure glaucoma treated in our hospital from March 2010 to October 2014 were selected, which were divided according to the double blind method into the observation group and the control group. Fifty-two cases(60 eyes)of the observation group were treated with trabeculectomy combined with compound Xueshuantong capsules, 48 cases(60 eyes)of the control group were treated with trabeculectomy. Visual acuity and visual field recovery in the two groups were compared.

RESULTS:At 3mo after operation, intraocular pressure(IOP)returned to normal, the visual acuity of observation group increased by 0.16±0.02, which of control group increased by 0.09±0.01, and the difference was significant(P<0.05).The total effective rate of visual acuity was 96.7% in the observation group and 83.3% in the control group, and the total effective rate of visual field was 96.7% in the observation group, and 83.3% in the control group. The total effective rates of visual acuity and visual field in the observation group were significantly higher than those in the control group(both P<0.05).The incidence of complications in the observation group(1.7%)was significantly lower than that in the control group(16.7%, P<0.05).

CONCLUSION:Trabeculectomy combined with compound Xueshuantong capsules for patients with acute angle-closure glaucoma can effectively improve the visual acuity, expand the scope of vision, and reduce the incidence of complications.