AIM: To discuss the application of anterior segment optic coherence tomography(AS-OCT)in the diagnosis of corneal ulcer.

METHODS: The cross linear scan was used in 88 patients(88 eyes)with corneal lesion by AS-OCT to gather the image data, observe the pathological changed tissue by measuring all layers for patients with initial inspection, providing important visual images and data for treatments. All the patients were followed up for 2mo.

RESULTS: Clear images with structure of all layers were obtained. It can provide the intuitive image data and scan the same position and show the changes during the treatment.

CONCLUSION: AS-OCT can discover the important condition immediately. It also can monitor course of disease dynamically, provide the intuitive image data for clinical treatment.