AIM:To evaluate the efficacy and safety of femtosecond laser micro incision lens extraction(SMILE)in the treatment of myopia.

METHODS: According to surgical treatment options 420 patients with myopia patients were(817 had eyes)divided into observation group(225 patients, 431 affected eyes)and control group(195 patients, 386 affected eyes). The observation group was treated with SMILE surgery correction, control group was treated with Bowman's layer of excimer laser in situ angular membrane keratomileusis(SBK)correction. The therapeutic effect of patients in two groups and the incidence rate of adverse reaction were comparativel analyzed.

RESULTS: After 1wk, 1mo and 3mo, there were no significant differences between the two groups. The difference was not statistically significant(P>0.05). Before and 1wk, 1mo, 3mo after operation, two groups of patients with corneal surface vertex height difference was not statistically significant(P>0.05). There was no significant difference between the two groups(P>0.05)in the preoperative and postoperative 3mo, the rupture time of the observation group was significantly longer than that in the control group(P<0.05). Preoperative and postoperative 1mo, 3mo, the two groups had no significant difference in the wet length of the Schirmer I test paper(P>0.05). Four eyes of the two groups had eye surgery source of corneal before surface clover grass difference, coma, spherical aberration and total higher order aberration compared the difference was not statistically significant(P>0.05).

CONCLUSION: The curative effect of SMILE surgery is similar to SBK surgery for myopia, but the early postoperative had better tear film stability.