AIM:To observe the clinical efficacy of trabeculectomy and endoscope-assisted vitrectomy combined with retinal photocoagulation in management of late neovascular glaucoma.

METHODS: Fifteen cases(15 eyes)with late neovascular glaucoma with above light perception vision in our hospital between Jul.2012 to Jul.2013 were treated with trabeculectomy and endoscope-assisted vitrectomy combined with retinal photocoagulation. The clinical data were retrospectively analyzed.

RESULTS: All the patients were followed up for 6mo. A total of 15 cases(15 eyes)of mean postoperative intraocular pressure(IOP)(12.53±3.73mmHg)(1mmHg=0.133kPa)at 1 week compared with preoperative IOP(58.81±5.9mmHg)was decreased obviously(P<0.05). One month(18.26±4.31mmHg), 3mo(17.06±3.65mmHg)and 6mo(16.13±3.66mmHg)mean postoperative IOP respectively compared with preoperative IOP(58.81±5.91mmHg)were significantly difference(P<0.05). The postoperative visual acuity improved in 2 eyes(13%), had no change in 11 eyes(73%)and decreased in 2 eyes(13%). During follow-up period, 4 eyes IOP were higher than 21mmHg and decreased to the normal range after the drug treatment. The pain of patients was alleviated. The iris neovascularization of all patients eliminated. No eyeball atrophy, retinal or choroidal detachment occurred during follow-up period.

CONCLUSION: Trabeculectomy and endoscope-assisted vitrectomy combined with retinal photocoagulation is a safe and effective therapy to reduce IOP, saving the residual vision and relieve suffering of patients with NVG.