AIM: To analyze and study the electrophysiological and clinical features of non-arteritic anterior ischaemic optic neuropathy(NAION)patients.

METHODS: Totally 68 cases(81 eyes)of NAION in our hospital from June 2015 to June 2016 were selected as the research object. All the subjects were divided into the control group(36 cases with 39 eyes), the observation group(32 cases with 42 eyes), according to the age, the age of the control group was at 50, the age of patients in the observation group was over 50. The demographic characteristics, clinical characteristics, risk factors, visual evoked potential and visual acuity of the two groups were compared and analyzed.

RESULTS: Clinical symptoms of the disease onset of the control group were occlusion, contralateral eye involvement, which was significantly lower than that of the patients in the observation group(P<0.05). Patients in the control group at 1° and 15 'spatial frequency were significantly better than those of the control group, there were obvious differences between groups(P<0.05). There was no significant difference between the control group and the observation group in the initial visual acuity(P>0.05). The final visual acuity of the control group was significantly better than that of the observation group(P<0.05).

CONCLUSION: For NAION patients, the clinical symptoms will be affected by age, occlusion, and contralateral eye involvement at the onset and other factors. The 1° and 15 'spatial frequency delay are relatively serious, and the final visual acuity is not very good. Thus, electrophysiological examination for the NAION patients help to diagnose the disease, clinicals should also strengthen the follow-up of NAION patients, reduce the contralateral eye.