局限性脉络膜凹陷39例的临床和OCT特征
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Clinical characteristics and OCT findings of focal choroidal excavation in 39 cases
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    摘要:

    目的:观察局限性脉络膜凹陷(focal choroidal excavation,FCE)的临床和光学相干断层扫描(OCT)特征。

    方法:收集2014-01/2016-01经OCT确定的FCE患者39例42眼,对其临床表现和OCT特点进行分析。所有患者均行系统的眼科检查,包括视力、屈光度、裂隙灯、检眼镜、OCT等。

    结果:患者39例中共有男24例26眼,女15例16眼(左眼20例,右眼16例,双眼3例)接受了检查。患者平均年龄50.4±16.7岁,屈光度为-2.51±2.60D,最佳矫正视力0.60±0.26,单眼发病36例(92%)。39例42眼患者中共46个病灶,其中紧密型37个(80%),分离型9个(20%)。病灶平均宽度为648.4±249.2μm,平均深度为128.0±50.4μm。黄斑中心凹下病灶16个(35%),其患者视力低于中心凹外FCE,有统计学差异(P<0.05)。3例患者合并脉络膜新生血管(CNV)、1例合并黄斑前膜、1例合并黄斑裂孔伴前膜、1例合并黄斑板层孔伴前膜。运用直线回归方法,分别计算患者年龄、视力和FCE的宽度、深度,发现两两间没有相关性(均P>0.05)。

    结论:FCE好发于轻中度近视的中老年人,单眼发生及紧密型多,可以合并黄斑裂孔、黄斑前膜以及脉络膜新生血管。FCE位于中心凹下可能影响患者视力,其发病原因需要进一步研究。

    Abstract:

    AIM: To observe the clinical features and optical coherence tomography(OCT)characteristics of focal choroidal excavation(FCE).

    METHODS: The medical records of patients with FCE determined by OCT during the period of time from January 2014 to January 2016 were reviewed and analyzed. All patients underwent systematic ophthalmic examinations, including visual acuity, refractive status, slit lamp, ophthalmoscopy, OCT, etc.

    RESULTS: Totally 24 men(26 eyes)and 15 women(16 eyes)were included in this study(20 left eyes, 16 right eyes, and 3 cases of bilateral eyes). The average age of patients was 50.4±16.7 years old. The range of patients refraction was(-2.51±2.60)D, and best corrected visual acuity(BCVA)was 0.60±0.26. Forty-six lesions were observed in 39 patients(42 eyes), with 37 cases(80%)of the conforming type and 9 cases(20%)of the nonconforming type. The average lesion width was 648.4±249.2μm and average depth was 128.0±50.4μm. BCVA in patients with the lesion under the fovea(16, 35%)was significantly lower than that with the lesion outside the fovea(P<0.05). FCE was complicated with choroidal neovascularization(CNV)in 3 cases, macular epiretinal membranes(ERM)in one case, macular hole and(epiretinal membrane)ERM in one case, macular lamellar hole and ERM in one case. There was no significant correlation among patient's age, visual acuity, FCE width and FCE depth in linear correlation analysis(P>0.05).

    CONCLUSION: FCE were mainly found in aging patients with mild and moderate myopia, mostly belonged to the conforming type in single eye. FCE was observed to complicate with macular hole, macular ERM and CNV. The visual acuity may be affected with FCE under the fovea. Further study on its etiology of FCE is needed.

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王振,王应利,周玉梅,等.局限性脉络膜凹陷39例的临床和OCT特征.国际眼科杂志, 2017,17(5):912-916.

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  • 收稿日期:2017-03-20
  • 最后修改日期:2017-04-12
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  • 在线发布日期: 2017-04-25
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