方法：选取2014-09/2016-09在本院门诊确诊的RP患者74例148眼，同时选取50例100眼正常人作为对照。对两组进行OCT检测和眼底拍照，观察患者视网膜黄斑部位的图像特征，并对患者眼底拍照的结果进行对比，测量黄斑中心凹颞侧面4mm位置、乳头黄斑束中点及黄斑中心凹厚度。

结果：对两组研究对象测量视网膜厚度显示，RP患者黄斑中心凹视网膜和中心凹颞侧部4mm厚度与正常人相比，差异无统计学意义(P>0.05)； RP患者乳头黄斑束中点厚度变薄，与正常人对比差异有统计学意义(P<0.05)； RP患者黄斑区OCT检测图像表征有5种类型：视网膜黄斑区域水肿者19例38眼； 视网膜色素脉络膜毛细血管层和上皮层变薄者18例36眼； 视网膜色素上皮层发生萎缩者12例24眼； 黄斑部视网膜厚度正常者12例24眼； 色素上皮层厚薄表现不一者13例26眼。

结论：OCT能在前期及时地发现RP患者黄斑部位的病变，帮助患者深入了解病情发展，为患者早期诊疗提供了临床依据。

METHODS: From September 2014 to September 2016, 74 patients(148 eyes)with retinitis pigmentosa diagnosed in our hospital were selected, and 50 healthy subjects(100 eyes)as normal controls; two groups received optical coherence tomography and fundus camera detection. The images of the macular were obtained to observe and measure the thickness of the macular fovea and at 4mm temporal side, the center of papillo macular bundle.

RESULTS:The results showed that: the thickness of the macular fovea and at 4mm temporal side of RP patients were the same as normal controls without statistically significant(P>0.05); the thickness of the center of papillo macular bundle was less than that of normal control with statistically significant(P<0.05). There were five types characteristics in OCT imges in RP patients: macular edema in 19 patients 38 eyes; retinal pigment epithelium and choroidal capillary thinning in 18 patients 36 eyes; retinal pigment epithelium atrophy in 12 patients 24 eyes; normal in 12 patients 24 eyes; different thickness of pigment epithelium layer in 13 patients 26 eyes.

CONCLUSION: Optical coherence tomography(OCT)can be used to detect the macular lesions in a timely manner, to help understanding the development of the disease, and provide the clinical basis for the early diagnosis and treatment of patients.