AIM: To evaluate the effect of orthokeratology on progression of juvenile myopia and analysis its influencing factors.

METHODS: Totally 97 patients(189 eyes, aging from 8 to 17 years old)who received orthokeratology lenses treatment in our hospital from January 2012 to December 2014, were followed up for 2a. The visual acuity, corneal curvature, diopter, and ocular axial length were observed. Factors of influencing myopia progress in juvenile were analyzed.

RESULTS: At 1mo after receiving orthokeratology contact lenses, the visual acuity and corneal curvature were changed compared with that of before(P<0.001). After 2a of receiving orthokeratology contact lenses, the difference was significant compared with baseline: spherical equivalence(-0.51±0.64D, t=10.864, P<0.001), axial length(0.33±0.31mm, t=14.879, P<0.001), corneal astigmatism(-0.25±0.43D, t=5.375, P<0.001). Statistic analysis showed that there was a negative correlation between the spherical equivalence and age, baseline of diopter or ocular axial length(P<0.05).

CONCLUSION: Orthokeratology can effectively improve the visual acuity of patients. Although there is slightly progression in diopter and ocular length after 2a of wearing orthokeratology contact lenses. Orthokeratology is an effective treatment on controlling progression of juvenile myopia, especially in the elder children who with the longer basic axial length and the greater diopter.