AIM: To observe the clinical effect of the tonifying kidney pills with mingmuwuzi treating evaporative dry eyes.

METHODS: This study adopted the positive drug control, prospective study, random number remainder grouping method to 65 cases of outpatient patients diagnosed with evaporative dry eyes which were divided into the treatment group 32 cases(64 eyes)and the control group 33 cases(66 eyes). The treatment group took the decoction of kidney pills with mingmuwuzi, combined with sodium hyaluronate eye drops. The control group simply use sodium hyaluronate eye drops, both group were set to 4wk for a course of treatment. To observe the symptoms and signs of two groups before and after the treatment, the change of the evaluation index and curative effect were evaluated.

RESULTS: The effectiveness of the treatment group was 87.5%, the control group was 78.8%, the difference was statistically significant(z=-3.149, P<0.05).

CONCLUSION: The treatment of the kidney pills with mingmuwuzi combined with sodium hyaluronate eye drops to evaporative dry eyes is more effective than the simple use of sodium hyaluronate eye drops.