AIM: To analyze curative effect of laser treatment for diabetic retinopathy(DR).

METHODS: A total of 100 patients(136 eyes)with DR who were admitted to our hospital during January 2015 to December 2016 were enrolled in the study. All patients were given 532nm laser treatment. Changes of visual acuity and the incidence of complications were statistically analyzed after treatment, and the macula central fovea retinal thickness and hemodynamic changes of affected eyes were compared before and after treatment. The effects of laser treatment were compared among patients with different types of diabetes, patients in different DR stages and patients with different glycosylated hemoglobin(HbAlc)levels.

RESULTS: After treatment, the macula central fovea retinal thickness, end diastolic velocity(EDV), pulsatility index(PI)and central retinal artery(CRA), mean flow velocity(Vm)significantly decreased(P<0.05). After treatment, there were 2 cases(2 eyes)of bleeding and 2 cases(2 eyes)of tractional retinal detachment. The effective improvement rate of visual acuity was 83.1%. There were significant differences in the improvement rate of visual acuity among patients with different types of diabetes \〖type 1(60.0%)vs type 2(84.9%)\〗, patients in different DR stages \〖preproliferative diabetic retinopathy(NPDR)92.3%, early proliferative stage(PDR)85.1%, high-risk PDR 54.2%\〗 and patients with different HbAlc levels(< 8% 91.8% vs ≥8% 73.0%)(P<0.05).

CONCLUSION: The 532nm laser treatment is effective for DR. It can significantly improve the retinal hemodynamics and visual acuity and relieve macular edema. Types of diabetes mellitus, stages of DR and blood glucose control effect may affect the effects of laser treatment.