方法：选取27例53眼中高度近视患者(-3.25～-21.5D)表面麻醉下行2.8mm透明角膜切口的有晶状体眼后房型人工晶状体植入术，观察术后视力、眼压、角膜内皮细胞计数、术源性散光、拱高的变化，随访1mo。

结果：术前最佳矫正视力(BCVA，LogMAR)为0.05±0.18，术后1d最佳矫正视力为0.02±0.14，术后1wk最佳矫正视力为-0.05±0.11，术后1mo最佳矫正视力为-0.07±0.10，术前与术后1wk，1mo最佳矫正视力均有统计学差异(P<0.05)。术前角膜内皮细胞计数为2932.5±270.8个/mm²，术后1d角膜内皮细胞计数为2917.1±299.0个/mm²，术后1wk角膜内皮细胞计数为2902.5±288.6个/mm²，术后1mo角膜内皮细胞计数为2855.3±284.2个/mm²，术前术后角膜内皮数尚不能认为存在统计学差异。术前眼压为15.8±2.5mmHg，术后1d眼压为15.3±2.9mmHg，术后1wk眼压为17.4±5.8mmHg，术后1mo眼压为15.8±2.6mmHg，术前、术后1d，1wk，1mo眼压存在差异，行两两比较，术后1d与术后1wk眼压存在统计学差异(P<0.05)。术后1d术源性散光为0.74±0.39D，术后1wk术源性散光为0.57±0.28D，术后1mo术源性散光为0.44±0.21D，术源性散光相比，两两比较均有统计学差异(P<0.05)。术前患者前房深度为3.26±0.25mm。术后1d拱高为654.5±345.2μm，术后1mo拱高为683.0±211.7μm，术后1mo拱高与术后1d拱高相比，有统计学差异(P<0.05)。手术无严重并发症的发生。

结论：有晶状体眼后房型人工晶状体植入矫治中高度近视短期观察安全、有效、可预测性好，远期效果有待于进一步随访观察。

METHODS: Fifty-three eyes of 27 patients with moderate to high myopia(-3.25 to -21.5D)were received posterior chamber phakic intraocular lens implantation with 2.8mm clear corneal incision. Changes of visual acuity, intraocular pressure(IOP), counts of endothelial cells and surgically induced astigmatism at 1mo after surgery were observed.

RESULTS: The preoperative best corrected visual acuity(BCVA LogMAR)were 0.05±0.18, the postoperative BCVA at 1d were 0.02±0.14, the postoperative BCVA at 1wk were -0.05±0.11, the postoperative BCVA at 1mo were -0.07±0.10. The postoperative BCVA were statistically significant differences in different time(P<0.05). The preoperative endothelial cell count was 2932.5±270.8/mm², the postoperative endothelial cell count at 1d was 2917.1±299.0/mm²; the postoperative endothelial cell count at 1wk was 2902.5±288.6/mm²; the postoperative endothelial cell count at 1mo was 2855.3±284.2/mm². The postoperative endothelial cell count was not statistically significant differences in different time. The preoperative IOP was 15.8±2.5mmHg; the postoperative IOP at 1d was 15.3±2.9mmHg; the postoperative IOP at 1wk was 17.4±5.8mmHg; the postoperative IOP at 1mo were 15.8±2.6mmHg. The preoperative IOP was significantly different compared with postoperative IOP at 1d, 1wk and 1mo. The postoperative IOP at 1d and 1wk were statistically significant differences(P<0.05). The surgically induced astigmatism at 1d was 0.74±0.39D; the surgically induced astigmatism at 1wk was 0.57±0.28D; the surgically induced astigmatism at 1mo was 0.44±0.21D. The postoperative IOP were statistically significant differences in different time(P<0.05). The preoperative anterior chamber depth was 3.26±0.25mm; the postoperative central vault at 1d were 654.5±345.2μm; the postoperative central vault at 1mo were 683.0±211.7μm. The postoperative central vault were significantly different between that at 1d and 1mo after operations. Operations went without serious complications.

CONCLUSION: Posterior chamber phakic intraocular lens implantation for moderate to high myopia were safe, effective and predictability. But long-term effect remains needed to be further follow-up.