AIM:To compare and analyze the diagnostic value of iris fluorescein angiography(IFA)combined with fundus fluorescein angiography(FFA), indocyanine green angiograph(ICGA), fundus fluorescein angiography in the diagnosis of early diabetic retinitis(DR).

METHODS: Totally 70 patients(136 eyes)with early diabetic retinopathy enrolled in our hospital from August 2015 to August 2016 were selected in this study. All patients were respectively treated with ICGA, FFA and IFA+FFA, and the detection results of three kinds of imaging methods were analyzed.

RESULTS: There were 120 pathological eyes(88.2%)were detected by FFA, 124 pathological eyes(91.2%)were detected by ICGA, 130 pathological eyes(95.6%)were detected by IFA+FFA, and there was no significant difference in the detection rate between the three methods(P>0.05). FFA detected 48 eyes with neovascularization, 18 eyes with vitreous hemorrhage, 38 eyes with macular edema, 16 eyes without perfusion area; ICGA detected 49 eyes with neovascularization, 38 eyes with macular edema, 17 eyes with vitreous hemorrhage, 20 eyes without perfusion area; IFA+FFA detected 17 eyes with proliferative diabetic iridopathy(DI), 22 eyes with non-proliferative DI, 5 eyes with NVG, 92 eyes without DI.

CONCLUSION: In the diagnosis of early diabetic retinopathy, iris fluorescence angiography, fundus fluorescein angiography and indocyanine green angiography all have good diagnostic value, but IFA+FFA can detect the diabetic retinopathy in time and provide the help for the timely treatment.