AIM: To observe the changes of anterior and posterior corneal curvature and anterior chamber depth after small incision lenticule extraction(SMILE)for low and high myopic astigmatism.

METHODS: Sixty-three cases(88 eyes)undergone SMILE in our hospital were included. The patients were divided into two groups based on astigmatism degree: the Group A: -2.00D to -4.00D astigmatism, the Group B: -0.25D to -1.00D astigmatism. Patients were examined at 1wk, 1 and 3mo after operations. Visual acuity, intraocular pressure, refraction, corneal curvature and anterior chamber depth were recorded. The change of anterior and posterior corneal curvature and anterior chamber depth was compared. Spearman correlation analysis and independent t test were used for statistical analysis.

RESULTS: Surgery was done well in all patients without complications. No statistically significant difference was found between the two groups in posterior corneal curvature and anterior chamber depth preoperatively, postoperatively 7d,1 and 3mo(P>0.05). One week postoperatively, the anterior corneal curvature was statistically significant from that of preoperative in both groups(P<0.05), while there were no significant differences at 1 and 3mo after operation(P>0.05).

CONCLUSION: No significant change of anterior and posterior corneal curvature and anterior chamber depth was found after SMILE for correcting low and high myopic astigmatism. One week after SMILE the anterior corneal curvature become stable.