AIM:To observe the clinical effect of bilateral oblique muscle weakening on the A-V patterns strabismus correction, and dose-response relationship between bilateral oblique muscle weakening and A-V syndrome degree.

METHODS: Totally 70 patients(70 eyes)with A-V syndrome treated in our hospital from January 2012 to January 2016 were enrolled in this study, including 28 eyes of A sign and 42 eyes of V sign. All patients underwent bilateral oblique muscle reduction combined with horizontal rectus correction. The changes of the upper and lower strabismus were observed before and after operation, and the patients were followed up for 18mo. The successful rate of A-V sign and strabismus correction were observed and counted. In addition, the quantitative relationship between the degree of A-V and the degree of correction and the amount of residual after operation was compared and analyzed.

RESULTS: After operation, the oblique eye position angle difference of A-esotropia, A-exotropia, V- esotropia and V-exotropia were respectively -1.98^△±3.92^△, -2.25^△±4.88^△, 2.96^△±5.29^△, 1.91^△±4.67^△, the differences were significantly compared with preoperatively(P<0.05). The reduce amount after operation were 25.10^△±9.79^△, 24.29^△±8.63^△, 23.81^△±9.24^△, 22.79^△±8.95^△. After 18mo follow-up, the success rate of A sign correction was 96%(27/28), and the successful rate of V sign correction was 93%(39/42). A-V sign, the more the oblique angle before operation, the more the correction amount during the weakening of bilateral oblique muscle, and the postoperative oblique residual increased accordingly.

CONCLUSION: Bilateral oblique muscle weakening can effectively treat strabismus with A-V sign, and can significantly reduce the upper and lower ocular gradient. The upper and lower oblique angle of the A-V sign increase, and the corrected angle and residual volume increase with the quantitative relationship.