AIM: To investigate the risk factors of primary angle-closure glaucoma(PACG)by questionnaires.

METHODS: By 1:2 matched case-control study, we selected 30 primary angle-closure glaucoma in Department of Ophthalmology, Affiliated Hospital of Xiangnan University from January 2015 to January 2017 and other 60 cases, the latter were no common pathogenic factors of glaucoma.

RESULTS: Using SPSS 17.0 software for statistical analysis, single factor logistic regression analysis showed that living in rural areas, the low cultural level, high blood pressure, long time use the eye, hyperopia and asthenopia, disharmony of family relationship, family members with glaucoma were eight variables associated with the onset of PACG. Multifactor conditional logistic regression analysis showed five variables associated with the onset of PACG(P<0.05), including the place of residence, long time use the eye, hyperopia and asthenopia, family relationship.

CONCLUSION: PACG is affected by various pathogenic factors, and it is helpful to analyze risk factors to reduce the incidence of PACG.