AIM:To study the effects of orthokeratology, low concentration atropine and frame glasses on juvenile myopia prevention and control.

METHODS: A total of 120 juvenile patients(240 eyes)with mild to moderate myopia were chosen in our hospital from January 2016 to July 2016. They were divided into 3 groups voluntarily. Children in orthokeratology group(40 cases, 80 eyes)were treated with orthokeratology; children in low concentration atropine group(40 cases, 80 eyes)were treated with low concentration atropine; children in frame glasses group(40 cases, 80 eyes)were treated with frame glasses. After 18mo follow-up, refractive degree and ocular axial length of three groups were statistically analyzed.

RESULTS: After 18mo, diopters of children in orthokeratology group and atropine group were lower than those of children in frame glasses group(P<0.05). The diopter differences between before and after treatment of orthokeratology group and atropine group were lower than that of the frame glasses group(P<0.05), there was no significant differences between orthokeratology group and atropine group(P>0.05). The axial growth of children in orthokeratology group and atropine group were lower than those of children in frame glasses group(P<0.05). The axial length differences between before and after treatment of orthokeratology group and atropine group were lower than that of the frame glasses group(P<0.05); there was no significant differences between orthokeratology group and atropine group(P>0.05).

CONCLUSION: Both orthokeratology and low concentration atropine can effectively control the progress of diopter and axial length in juvenile myopia, and their curative effects were better than frame glasses. During the 18mo observation period, the curative effects of orthokeratology and atropine have no significant differences.