Abstract:AIM: To systematically review and assess the efficacy and safety of phacoemulsification combined with intraocular lens(IOL)implantation versus trabeculectomy for angle closure glaucoma with cataract.
METHODS: Databases including CNKI, CBM, WangFang, VIP, Medline, EMBASE, Cochrane library were searched to collect randomized controlled trails(RCTs)about phacoemulsification combined with intraocular lens implantation versus trabeculectomy. Cochrane collaboration's tool were used to assess the risk of bias of included studies and the meta-analysis was conducted by Revman 5.3 software.
RESULTS: Nine eligible studies involving 696 patients were included. The results of meta-analysis shows that: there were no significant differences between two groups in postoperative intraocular pressure(P>0.05). While phacoemulsification combined with intraocular lens implantation has lower complications rate(Z=4.32, P<0.0001).
CONCLUSION: Current evidence shows that phacoemulsification combined with intraocular lens implantation and trabeculectomy may has the similar efficacy for angle-closure glaucoma with cataract. But the former operation are more safer for patients.