目的：探讨清热化瘀方治疗非增殖期糖尿病视网膜病变(NPDR)的疗效。

方法：选取2016-06/2017-12期间于我院眼科就诊的中医辨证施治诊断为“瘀热阻络型”的NPDR患者84例84眼，根据随机数字表法分为对照组和试验组各42例，在常规降糖治疗的基础上，对照组患者采用羟苯磺酸钙胶囊治疗，试验组患者采用清热化瘀方治疗，疗程为6wk。观察两组患者治疗前后视力、眼底病变改善情况及临床疗效。

结果：治疗前，两组患者视力差异无统计学意义(P>0.05)； 治疗6wk后，试验组患者视力(0.21±0.11)明显优于对照组(0.30±0.13)，差异有统计学意义(P<0.05)。治疗6wk后，试验组患者眼底改善有效率和临床疗效有效率(78.6%和71.4%)均高于对照组(45.2%和40.5%)，两组患者眼底改善情况和临床疗效比较，差异均有统计学意义(P<0.05)。

结论：在传统降糖治疗的基础上，采用清热化瘀方治疗NPDR(瘀热阻络型)有较好的疗效，能够提高患者的预后视力，符合辨证施治，为NPDR的中医治疗提供了思路。

METHODS:We selected 84 cases of 84 eyes of NPDR patients diagnosed as “heat-blocking type” in the Department of Ophthalmology of our hospital during June 2016 to December 2017. According to the random number table method, 42 cases were divided into control group and experimental group respectively. On the basis of conventional hypoglycemic treatment, the control group was treated with calcium hydroxy benzene sulfonate capsules, and the observation group was treated with Qingre Huayu Recipe for 6wk. The improvement of visual acuity, fundus lesions and clinical efficacy before and after treatment were observed.

RESULTS:Before treatment, there was no significant difference in visual acuity between the two groups(P>0.05). After 6wk of treatment, the visual acuity of the experimental group(0.21±0.11)was significantly better than that of the control group(0.30±0.13), and the difference was statistically significant(P<0.05). After 6wk of treatment, the fundus improvement efficiency and clinical efficacy(78.6% and 71.4%)were higher in the experimental group than in the control group(45.2% and 40.5%). There were significant differences in the improvement of fundus and clinical efficacy between the two groups(P<0.05).

CONCLUSION:On the basis of traditional hypoglycemic treatment, Qingre Huayu Recipe has good curative effect on NPDR(heat-blocking type), which can improve the prognosis of patients. It is in line with syndrome differentiation and treatment, and provides ideas for Chinese medicine treatment of NPDR.