AIM: To evaluate the effect on accommodative functions after femtosecond laser assisted LASIK(FEMTO LASIK)for myopic anisometropia.

METHODS: A respective serial case observational study was designed. Thirty-five patients(70 eyes)with myopic anisometropia treated by FEMTO LASIK were included in the study. Their uncorrected distance visual acuity, distance spherical equivalent, the difference of binocular diopter and accommodative functions including amplitude of accommodation, negative relative accommodation, positive relative accommodation and lag of accommodation were measured three times(before surgery, 1mo and 3mo after surgery).

RESULTS: At 1mo and 3mo after surgery, uncorrected distance visual acuity was improved significantly, distance spherical equivalent and the difference of binocular diopter were significantly decreased. Amplitude of accommodation and positive relative accommodation were improved at 3mo after surgery. The differences were statistically significant. There was no statistically significant difference of negative relative accommodation and lag of accommodation between these three times.

CONCLUSION: FEMTO LASIK for the correction of myopic anisometropia is an effective and safe procedure. The surgery may have no adverse influence on patients' accommodative function. It would be helpful for recovery of the binocular coordinate accommodative function.