Amblyopia is defined as a decrease in visual acuity that results from abnormal binocular interaction or visual deprivation during critical period of the visual cortex, which cause a variety of visual functions damage. With the development of science and technology, amblyopia treatment has new concept. The new method of amblyopia treatment is occlusion therapy based on corrected refraction, followed by visual function training and pharamacological therapy, instead of traditional treatment which contians only refraction correction and patching therapy. Correction of refractive error is no longer limited to use spectacles, also provided with contact lenses, corneal refractive surgery and intraocular refractive surgery. In addition to using patching, occlusion therapy can use Bangerter filters, contact lenses and LED liquid crystal glasses. The training of visual function aimed to improve three-level visual function and restore visual cortical plasticity, which is especially important in the adult amblyopia. Levodopa and citicoline drugs can be added to occlusion therapy in order to reach a better outcome. We should design the fittest treatment plan according to the individual situation of the patients within varied of methods, adopting diversified combination, personalized therapy.