AIM: To investigate the efficacy and independent influencing factors of YAG laser combined with RS drainage tube in the treatment of lacrimal duct obstruction.

METHODS: Retrospective analysis of the cases of 250 patients with lacrimal duct obstruction treated by laser combined drainage tube in our hospital from 2015-01/2018-01, summarized the efficacy and analyzed the independent factors of efficacy.

RESULTS: The total effective rate of clinical treatment was 87.9%; course of disease(OR=8.654, 95% CI: 3.740-20.023), frequency of lacrimal passage(OR=3.480, 95% CI: 2.128-5.691), length of lacrimal duct obstruction(OR=0.518, 95% CI: 0.238-1.131), extubation time(OR=0.386, 95% CI: 0.237-0.628)and initial surgery(OR=14.717, 95% CI: 10.798-20.059)were the independent factor influencing the efficacy.

CONCLUSION: YAG laser combined with RS disposable drainage tube is effective in the treatment of lacrimal duct obstruction. Early treatment, avoiding multiple operations, proper irrigation of lacrimal passage after operation, and controlling extubation time, which are beneficial to improve the curative effect and improve the prognosis of patients.