目的：通过比较配戴减少周边远视离焦设计的框架眼镜(AMSPL)和普通球柱镜框架眼镜(SPL)对近视儿童眼部各参数的影响，确定AMSPL安全性和有效性。

方法：随机抽取2017-07/2018-02于我院眼科中心配戴AMSPL的8～14岁近视儿童50例作为AMSPL组，同样抽取年龄、近视程度及配镜时间相当的SPL配戴者资料50例作为SPL组。检查两组患者眼压、睫状肌麻痹下的屈光状态、远距水平隐斜、近距水平隐斜、AC/A等双眼协动参数。

结果：AMSPL组儿童配戴初期舒适程度略低于SPL组，主要为周边视物模糊，但1mo后两者无差异； AMSPL组屈光不正度数年平均增长-0.62±0.50D，SPL组年平均增长-0.77±0.48D(P=0.072)； 对于8～10岁近视儿童AMSPL组屈光不正度数年平均增长(-0.71±0.41D)低于SPL组(-1.05±0.39D)，差异具有统计学意义(t=2.164，P=0.041)； AMSPL组和SPL组远距水平隐斜、近距水平隐斜、AC/A等双眼协动参数无差异(P>0.05)。

结论：配戴AMSPL能在一定程度上延缓近视发展，尤其对于低龄近视儿童(8～10岁)效果较明显。配戴AMSPL与SPL相比眼部参数无明显变化，这表明近视儿童配戴AMSPL与SPL同样安全。

METHODS: Totally 50 children aged 8 to 14 years wearing spectacle lens designed to reduce peripheral hyperopic defocus(AMSPL)were collected into the AMSPL group, and other 50 children in the same age, the same degree of myopia and the same glasses time wearing standard design control lens(SPL)were selected into normal control group randomly(SPL group). We reviewed their documents and exam all patients. The examination include intraocular pressure, refraction under cycloplegia, distant strabismus and near strabismus, AC/A ratio.

RESULTS: The children wearing spectacle lens designed to reduce peripheral hyperopic defocus(AMSPL)had lower feeling of comfort than SPL group, mainly in peripheral vision confused, but no difference between them 1mo later. The AMSPL group's average growth of refractive error is -0.62±0.50D, the SPL group's average growth of refractive error is -0.77±0.48D(P=0.072). In myopic children aged 8 to 10 years, the AMSPL group's average development of refractive error is -0.71±0.41D, lower than the SPL group that of -1.05±0.39D, the difference was significant(t=2.164, P=0.041). Between the two groups, there was no significant difference(P>0.05)in visual parameters of distant strabismus, near strabismus, AC/A ratio.

CONCLUSION: Wearing spectacle lens designed to reduce peripheral hyperopic defocus(AMSPL)can delay the progression of myopia to a certain extent, especially for myopic children aged 8 to 10 years. It suggests that wearing AMSPL has the same safety with SPL for myopic children.