AIM: To study the efficacy of AMSPL on myopia control, and confirm the security of wearing AMSPL, through comparing the impacts on visual parameters between myopic children wearing spectacle lens designed to reduce peripheral hyperopic defocus(AMSPL)and myopic children wearing the standard design control lens(SPL).

METHODS: Totally 50 children aged 8 to 14 years wearing spectacle lens designed to reduce peripheral hyperopic defocus(AMSPL)were collected into the AMSPL group, and other 50 children in the same age, the same degree of myopia and the same glasses time wearing standard design control lens(SPL)were selected into normal control group randomly(SPL group). We reviewed their documents and exam all patients. The examination include intraocular pressure, refraction under cycloplegia, distant strabismus and near strabismus, AC/A ratio.

RESULTS: The children wearing spectacle lens designed to reduce peripheral hyperopic defocus(AMSPL)had lower feeling of comfort than SPL group, mainly in peripheral vision confused, but no difference between them 1mo later. The AMSPL group's average growth of refractive error is -0.62±0.50D, the SPL group's average growth of refractive error is -0.77±0.48D(P=0.072). In myopic children aged 8 to 10 years, the AMSPL group's average development of refractive error is -0.71±0.41D, lower than the SPL group that of -1.05±0.39D, the difference was significant(t=2.164, P=0.041). Between the two groups, there was no significant difference(P>0.05)in visual parameters of distant strabismus, near strabismus, AC/A ratio.

CONCLUSION: Wearing spectacle lens designed to reduce peripheral hyperopic defocus(AMSPL)can delay the progression of myopia to a certain extent, especially for myopic children aged 8 to 10 years. It suggests that wearing AMSPL has the same safety with SPL for myopic children.