目的：比较隐形遮盖镜与压抑膜疗法治疗大龄弱视患者的疗效。

方法：前瞻性研究。选取2015-06/2016-12于我院就诊的10～14岁单眼弱视患者112例112眼，其中应用压抑膜疗法治疗者55例(A组)，应用隐形遮盖镜疗法者57例(B组)。评估两组患者的治疗依从性和疗效，观察两组患者治疗前后矫正视力的变化情况。

结果：治疗3、6、12mo，A组患者治疗依从性(98.2%、96.4%、92.7%)与B组(94.7%、91.2%、89.5%)无明显差异(均P>0.05)，但治疗有效率(27.8%、50.9%、76.5%)均明显低于B组(46.3%、71.2%、92.2%)，且B组患者弱视眼矫正视力均优于A组(P<0.05)。治疗12mo，A组患者总治愈率和实际治愈率(52.7%和56.9%)均明显低于B组(71.9%和80.4%)。

结论：隐形遮盖镜疗法治疗10岁以上单眼弱视，弱视眼视力提高速度和治愈率均优于压抑膜遮盖疗法。

METHODS: Prospective study. Totally 112 cases(112 eyes)of monocular amblyopia aged 10-14 years were selected from June 2015 to December 2016 in our hospital. Among them, 55 cases(Group A)were treated with depressant membrane therapy and 57 cases(Group B)were treated with invisible concealer. The treatment compliance and efficacy of the two groups were evaluated, and the changes of corrected visual acuity before and after treatment were observed.

RESULTS: For 3, 6 and 12mo, there was no significant difference in treatment compliance between group A(98.2%, 96.4%, 92.7%)and group B(94.7%, 91.2%, 89.5%)(all P>0.05), but the effective rate of treatment(27.8%, 50.9%, 76.5%)was significantly lower than that of group B(46.3%, 71.2%, 92.2%), and the amblyopic corrected visual acuity of group B was better than that of group A(P<0.05). After 12mo treatment, the total and actual cure rates of group A(52.7% and 56.9%)were significantly lower than those of group B(71.9% and 80.4%).

CONCLUSION: The treatment of monocular amblyopia over 10 years old with invisible occlusion mirror is superior to that of depressor membrane occlusion in improving visual acuity and curing rate.