AIM: To investigate the retinal thickness, choroidal thickness and optic disc nerve fiber layers thickness in high myopia amblyopia eyes and high myopia eyes with the similar diopter by using enhanced depth imaging optical coherence tomography(EDI-OCT).

METHODS:Nineteen Chinese children, 26 eyes were recruited. Those patients were divided into high myopia amblyopia group(11 eyes)and high myopia group(15 eyes). The thickness in the retina and choroid in different regions, as well as the thickness of optic disc nerve fiber layer were measured by EDI-OCT.

RESULTS: The retinal thickness at the 1.0mm, 1.5mm, 2.0mm, 2.5mm, 3.0mm to the fovea, in most directions, retinal thicknesses were statistically different between the two groups(P<0.05). At the 3.0mm inferior to the fovea, the choroidal thickness in high myopia amblyopia was significantly thinner than high myopia(P=0.012). In the optic disc nerve fiber layer, there was no statistical difference between high myopia amblyopia and high myopia(P>0.05).

CONCLUSION: In the same diopter range, the retinal thickness around the fovea in the high myopia amblyopia was significantly thinner than high myopia, and the occurrence and development of amblyopia may be involved in its change process.