AIM: To analyze the risk factors of early bleeding after 23G vitrectomy for proliferative diabetic retinopathy(PDR).

METHODS: A retrospective analysis was made on the clinical data of 100(100 eyes)PDR patients who were underwent 23G vitrectomy from June 2016 to January 2018. According to whether vitreous hemorrhage occurred in the early stage of operation(within 1mo), the patients were divided into early vitreous hemorrhage group(27 cases)and non vitreous hemorrhage group(73 cases). The risk factors of early vitreous hemorrhage were analyzed.

RESULTS: There were significant differences in age, preoperative anti-vascular therapy, preoperative fibrovascular membrane proliferation, intraoperative optic disc neovascularization hemorrhage and intraoperative gas injection between the two groups(P<0.01). Preoperative fibrovascular membrane proliferation and intraoperative optic disc neovascularization hemorrhage were independent risk factors for early postoperative hemorrhage.

CONCLUSION: Early vitreous hemorrhage after 23G vitrectomy for PDR mainly occurs in patients with severe fundus lesions. Preoperative fibrovascular membrane proliferation and intraoperative optic disc neovascularization hemorrhage increase the risk of vitreous hemorrhage.