两种内界膜剥离方式治疗MHCI<0.7特发性黄斑裂孔的疗效
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Therapeutic effect of two methods of internal limiting membrane dissection on MHCI < 0.7 idiopathic macular hole
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    摘要:

    目的:观察玻璃体切割术中不同内界膜剥离方式治疗黄斑裂孔闭合指数(MHCI)<0.7特发性黄斑裂孔(IMH)的临床效果。

    方法:将2014-05/2017-05收治的MHCI<0.7 IMH患者88例88眼随机分为A组(44眼,行扩大内界膜剥离术)和B组(44眼,行标准内界膜剥离术),观察两组患者黄斑裂孔闭合情况、最佳矫正视力(BCVA)、中心暗点及并发症发生情况。

    结果:术后6mo,A组患者黄斑裂孔闭合率明显高于B组(91% vs 75%,P<0.05),BCVA优于B组(0.47±0.05 vs 0.74±0.14,P<0.05),中心暗点眼数占比低于B组(4% vs 23%,P<0.05),且两组患者并发症发生率无明显差异(11% vs 9%,P>0.05)。

    结论:临床治疗MHCI<0.7的IMH采用扩大内界膜剥离术较标准内界膜剥离术疗效更突出,前者视网膜功能恢复效果更佳。

    Abstract:

    AIM: To observe the clinical effects of different methods of internal limiting membrane peeling in vitrectomy in treatment of idiopathic macular hole(IMH)with macular hole closure index(MHCI)<0.7.

    METHODS: Totally 88 patients(88 eyes)with MHCI<0.7 IMH admitted from May 2014 to May 2017 were randomly divided into group A(44 eyes underwent extended internal limiting membrane dissection)and group B(44 eyes underwent standard internal limiting membrane dissection). The closure of macular hole, best corrected visual acuity(BCVA), central scotoma and complications were observed between the two groups.

    RESULTS: At 6mo after operation, the closure rate of macular hole in group A was significantly higher than that in group B(91% vs 75%, P<0.05). At 6mo after operation, BCVA in group A was better than that in group B(0.47±0.05 vs 0.74±0.14, P<0.05). The percentage of central scotoma eyes was lower than that in group B(4% vs 23%, P<0.05), but there was no significant difference in the incidence of complications between the two groups(11% vs 9%, P>0.05).

    CONCLUSION: Extended internal limiting membrane dissection is more effective than standard internal limiting membrane dissection in the treatment of IMH with MHCI < 0.7, and the former is better for the recovery of retinal function.

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黄惠嫔,王艳菊,柯瑞莉,等.两种内界膜剥离方式治疗MHCI<0.7特发性黄斑裂孔的疗效.国际眼科杂志, 2019,19(7):1170-1173.

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  • 收稿日期:2019-01-23
  • 最后修改日期:2019-06-05
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  • 在线发布日期: 2019-06-21
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