AIM: To observe the effectiveness and safety of the active-fluidics configuration with Centurion phacoemulsifier in cataract surgery.

METHODS: One hundred and thirty-three eyes with Ⅱ-Ⅳ grades cataracts were enrolled in this randomized prospective study from October to December 2018. They were divided into two groups, the experimental group used active-fluidics configuration for cataract surgery, while the control group used gravity-fluidics configuration. Cumulative dissipated energy(CDE), aspiration time(AT)and estimated fluid used(EFU)of each patient were recorded during the operation, endothelial cell density(ECD)and central corneal thickness(CCT)were measured before and one day after operation.

RESULTS: The CDE, AT and EFU were significantly lower with the active-fluidics configuration than with the gravity-fluidics configuration(P<0.05); ECD was slightly decreased and CCT was slightly increased in both groups 1d after operation, but there was no difference between the two groups(2056.06±308.10cells/mm² vs 1997.26±297.55cells/mm², 532.75±12.02μm vs 531.02±13.00μm; P>0.05). No serious ocular adverse events related to the study devices or device deficiencies were observed.

CONCLUSION:Centurion active-fluidics configuration can maintain constant intraocular pressure during the operation, improve the stability of anterior chamber effectively. So it is safer and more efficient than traditional gravity-fluidics configuration.