[关键词]
[摘要]
糖尿病视网膜病变(DR)是继发于糖尿病的慢性视网膜微血管病变，可致糖尿病患者视力永久丧失。DR的发生与视网膜微血管功能障碍、视网膜组织水肿、出血和继发性新血管增殖有关。有研究显示，在糖尿病患者的脂肪组织、肝脏和肾脏中均发现内脏脂肪素高表达，并且该因子可能存在于视网膜组织中，对DR的发生发展具有一定调控性作用。本综述以内脏脂肪素与DR的相关研究为依据，对内脏脂肪素与DR的关系作论述。
[Key word]
[Abstract]
Diabetic retinopathy(DR)is a chronic retinopathy secondary to diabetes that can cause permanent loss of vision in patients with type 1 and type 2 diabetes. The occurrence of DR is associated with retinal microvascular dysfunction, retinal tissue edema, bleeding, and secondary neovascular proliferation. Studies have shown that patients with diabetes have high expression of visfatin in adipose tissue, liver and kidney, and that the factor may be present in retinal tissue, which has a certain regulatory effect on the development of diabetic retinopathy. This review focuses on the relationship between visfatin and diabetic retinopathy.
[中图分类号]
[基金项目]
内蒙古自治区自然科学基金项目(No.2014MS0865); 内蒙古自治区人民医院青年基金项目(No.201558)
