方法：回顾性非随机对照研究。选取2018-01/2019-01在我院确诊的IMH患者76例76眼，按手术方式分为两组， 其中38眼行PPV联合无染色剂下ILMP、空气填充术(A组)，38眼行PPV联合无染色剂下ILMP、笛针吸引、空气填充术(B组)。术后随访6mo以上，观察两组患者黄斑裂孔闭合、最佳矫正视力(BCVA)及并发症发生情况。

结果：术后6mo，A组患者黄斑裂孔闭合率和BCVA提高率均显著低于B组(84% vs 100%，76% vs 95%，均P<0.05)。随着术后时间的推移，两组患者BCVA逐渐改善，且术后7、14d，1、3、6mo B组患者BCVA优于A组(均P<0.05)。术后随访期间，两组患者均未出现严重并发症。

结论：无染色剂下ILMP联合笛针吸引治疗IMH临床疗效确切，在裂孔闭合率及BCVA改善方面明显优于单纯ILMP组。

METHODS: A retrospective non-randomized case study on 76 patients(76 eyes)were diagnosed with IMH in our hospital from January 2018 to January 2019, 38 eyes were treated with PPV combined with ILMP and air tamponade without staining(group A), the remaining 38 eyes were treated with PPV combined with ILMP, needle drawing the Hole edge and air tamponde without staining(group B). The patients were followed up for more than 6mo, the macular hole closure, the best correct visual acuity(BCVA)and postoperative complication were analyzed in the two groups.

RESULTS: At 6mo after surgery, the closure rate of MH and BCVA improvement rate in group A were significantly lower than those in the group B(84% vs 100%, 76% vs 95%, P<0.05). With the passage of postoperative time after surgery, the BCVA of two groups of patients gradually improved, and the BCVA of group B was better than that of group A at 7, 14d, and 1, 3, 6mo after surgery(P<0.05). There were no postoperative complications in two groups.

CONCLUSION: PPV combined with ILM peeling without staining agent and flute needle drawing is effective in treating IMH, which is better than ILM-P group in both closure rate and BCVA improvement.