目的：探讨视网膜激光光凝引起不良反应的影响因素及应对策略。

方法：回顾性分析2017-06/2019-05于我院行视网膜激光光凝治疗的眼底病患者1 165例的不良反应发生情况。

结果：本研究纳入患者1 165例中发生不良反应者50例(4.29%)，其中恶心、呕吐者13例(1.12%)，头晕、胸闷、冒冷汗者21例(1.80%)，打哈欠、困倦无力者4例(0.34%)，晕厥12例(1.03%)，无死亡病例。男女患者不良反应发生率无差异(3.68% vs 5.14%，χ²=1.474，P=0.225)； 不同年龄段患者不良反应发生率有差异(χ²=48.817，P<0.05)，40岁以下患者不良反应发生率高于40岁及以上患者，且40岁以下男性患者不良反应发生率明显低于女性患者(8.46% vs 18.60%，χ²=6.094，P=0.014)； 不同光凝范围的患者不良反应发生情况也不相同。

结论：视网膜激光光凝术治疗不同年龄段眼底疾病患者术后不良反应发生率及程度不一，术前应详细了解患者病史及精神状态，对存在高危因素的患者及可能发生的严重反应做好及时救治的准备，以确保患者的生命安全。

METHODS: Retrospective analysis of 1 165 cases of adverse reactions in patients with retinal laser photocoagulation in our hospital.

RESULTS: The present study included 50 patients with adverse reactions in 1 165 patients(4.29%), including 13 patients with nausea and vomiting(1.12%), 21 patients with dizziness, chest tightness, cold sweat(1.80%), 4 cases with yawning and drowsiness(0.34%), 12 cases with syncope(1.03%), and no death. There was no difference in the incidence of adverse reactions between men and women(3.68% vs 5.14%, χ²=1.474, P=0.225); there was a difference in the incidence of adverse reactions among patients of different ages(χ²=48.817, P<0.05)and under 40. The incidence of adverse reactions was higher than that of patients aged 40 and older, and the incidence of adverse reactions in men under 40 was significantly lower than that in women(8.46% vs 18.60%, χ²=6.094, P=0.014). The adverse reactions of patients with different fundus diseases were different.

CONCLUSION: The incidence and degree of postoperative adverse reactions in patients with fundus diseases treated by retinal laser photocoagulation are different, so we should understand the history and mental state of the patients in detail before operation, and prepare the patients with high risk factors and possible serious reactions in time to ensure the safety of the patients.