[关键词]
[摘要]
结膜重建常用于各种化学热烧伤所导致的严重结膜缺损,而组织工程结膜能有效解决在结膜移植中自体结膜移植材料缺乏及异体结膜移植材料存在免疫排斥反应等难题。具有良好生物相容性及足够生物力学强度的支架材料是构建组织工程结膜的重要条件。本文对组织工程结膜支架材料的最新研究进展及目前存在的问题进行总结。
[Key word]
[Abstract]
Conjunctival reconstruction is commonly used in severe conjunctival defect caused by chemical or thermal burns. The problems of conjunctival transplantation, including shortage of autogenous conjunctiva and immunological rejection of xenogenous conjunctiva or materials, could be solved by tissue engineering conjunctiva. A scaffold material with well biocompatibility and sufficient biomechanical property plays a critical role in the construction of tissue engineering conjunctiva. In this review, the latest research progress and the existing problems of scafflod materials in tissue engineering conjunctiva were summarized.
[中图分类号]
[基金项目]
国家自然科学基金面上项目(No.81870637)