Ocular Demodex infection is mainly manifested as ocular surface diseases, including meibomian gland dysfunction, dry eye disease, Demodex blepharitis, chalazion, keratoconjunctivitis, etc. The diagnosis is relatively simple and can be realized under the microscope, but it is easy to be misdiagnosed due to the subjective and objective factors such as similar symptoms, missing examination, experience diagnosis and treatment. There are many treatment methods for ocular Demodex infection, including external tea tree oil and other plant extracts, oral or external drugs, physical therapy(represented by strong pulse light therapy, moxibustion therapy), combined therapy, etc. In this paper, we reviewed the diagnosis and treatment of Demodex related ocular surface diseases, and discussed the latest research trends of this disease.

国家自然科学基金面上资助项目(No.30772824,81574031); 中医药防治五官科疾病湖南省重点实验室建设项目(No.2017TP1018); 国家中医药管理局中医眼科学重点学科建设项目(No.ZK1801YK015); 湖南省中医药防治眼耳鼻咽喉疾病与视功能保护工程技术研究中心建设项目(No.2018TP2008); 湖南省中医五官科学重点学科建设项目; 湖南中医药大学中医学国内一流建设学科项目