[关键词]
[摘要]
近年来，干细胞在眼科领域的研究及应用受到高度关注，胚胎干细胞(ES)、成体干细胞能够被定向诱导分化成视网膜色素上皮细胞，由此可获得转分化的大量的视网膜色素上皮细胞源，通过体内干细胞及视网膜色素上皮细胞移植有望应用于各种视网膜退行性疾病的细胞替代治疗。本文就各种干细胞诱导分化为视网膜色素上皮细胞的途径及应用进行探讨。
[Key word]
[Abstract]
In recent years, stem cell research and application in the field of ophthalmology has been highlighted, embryonic stem cells and adult stem cells can be targeted induced to differentiate into retinal pigment epithelial cells(RPE cells), which can obtain transdifferentiation of RPE cells source, through the body stem cells and retinal pigment epithelium cells transplantation is expected to be used in a variety of alternative treatment of the degenerative diseases of the retina. In this paper, the methods and application of various stem cells induced differentiation into RPE cells were discussed.
[中图分类号]
[基金项目]
国家自然科学基金资助项目(No.81770948); 福建省科技创新领军人才基金资助项目(No.2016B011)
