AIM: To evaluate the efficacy of 25G⁺vitrectomy combined with fixation by sclera suture through vitreous cavity in the treatment of Bigbag IOL-bag complex dislocation of high myopia.

METHODS: Totally 13 patients(15 eyes)of high myopia with Bigbag IOL-bag complex dislocation enrolled in this respective study. All cases underwent 25G⁺ vitrectomy. The vitreous body wrapped around the complex was cleaned and the heavy water was injected into the vitreous cavity to make the IOL float to the pupil area. The IOL was suspended and fixed on the sclera through the vitreous cavity. One case(1 eye)with macular hole was treated with inner limiting membrane peeling combined with gas injection, and laser photocoagulation was performed on 1 case(1 eye)with retinal hole.

RESULTS: The postoperative intraocular pressure(IOP)(16.75±6.71mmHg)was similar to the preoperative IOP(17.45±6.81mmHg)within normal limits(t=1.635, P=0.360), and best corrected visual acuity(BCVA, LogMAR)at 1wk postoperatively were ameliorated from 1.31±0.33 to 1.03±0.29(t=4.126, P=0.017). No significant difference was noted between preoperative(2388.93±405.04cell/mm²)and postoperative(2345.92±399.59cell/mm²)counting of corneal endothelial cell(t=2.323, P=0.279). Corneal transparency and position of IOL kept normal and no complications such as choroid detachment, retinal detachment, bleeding or secondary glaucoma was recorded in the follow-up period.

CONCLUSION: 25G vitrectomy combined with fixation by sclera suture through vitreous cavity contributes to the anatomical repair and visual function recovery of patients of high myopia with Bigbag IOL-bag complex dislocation.