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[摘要]
目的:分析白内障超声乳化联合人工晶状体(IOL)植入术治疗原发性闭角型青光眼(PACG)的有效性及影响因素。方法:回顾性分析2017-01/2018-12在本院接受白内障超声乳化联合IOL植入术治疗的PACG患者75例75眼的临床资料,统计其眼压、最佳矫正视力(BCVA)、眼前节参数及并发症发生情况,并采用多因素Logistic回归分析影响PACG患者白内障超声乳化联合IOL植入术疗效的危险因素。结果:与术前比较,PACG患者术后眼压均下降,BCVA均改善(P<0.05); 术后中央前房深度(ACD)、房角开放距离(AOD500)、小梁虹膜夹角(TIA500)、房角隐窝面积(ARA)较术前显著上升(P<0.05); 多因素Logistic回归分析显示,慢性PACG、术前眼压是PACG患者白内障超声乳化联合IOL植入术疗效的危险因素(P<0.05)。结论:白内障超声乳化联合IOL植入术治疗PACG疗效及安全性俱佳,但需重视术前眼压控制,对慢性PACG患者或应慎重考虑是否需行该术式。
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[Abstract]
AIM: To analyze the effectiveness and influencing factors of phacoemulsification combined with intraocular lens(IOL)implantation in the treatment of primary angle-closure glaucoma(PACG). METHODS: Clinical data of 75 patients(75 eyes)with PACG who received phacoemulsification and IOL implantation in our hospital from January 2017 to December 2018 were retrospectively analyzed. Postoperative intraocular pressure(IOP), best-corrected visual acuity(BCVA), changes of anterior segment and incidence of complications were counted. The patients were grouped by efficacy, and multivariate Logistic regression analysis was performed to analyze the risk factors influencing the effectiveness of phacoemulsification and IOL implantation in patients with PACG. RESULTS: Postoperative IOP of patients with PACG was decreased while BCVA was increased, and there were statistically significant differences compared with those before operation(P<0.05). Central anterior chamber depth(ACD), angle opening distance(AOD500), trabecular iris angle(TIA500)and angle recess area(ARA)were increased significantly compared with those before operation(P<0.05). Multivariate Logistic regression analysis showed that chronic PACG and preoperative IOP were independent risk factors for efficacy of phacoemulsification and IOL implantation in patients with PACG(P<0.05). CONCLUSION: Phacoemulsification combined with IOL implantation has good efficacy and safety in the treatment of PACG. However, it is necessary to pay attention to preoperative IOP control. What's more, it should be carefully considered whether this operation is necessary for patients with chronic PACG.
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