Corneal refractive surgery is a method of correcting refractive errors such as myopia, hyperopia and astigmatism through corneal surgery. Refractive regression can often be seen in clinical practice, that is, refractive errors occur again after surgery. Refractive regression and the consequent poor visual quality often trouble patients. So far, different types and methods of corneal refractive surgery have the problem of refractive regression. It is believed that refractive regression is mainly related with epithelium thickening and change of corneal biomechanics. Refractive regression could be predicted and avoided by preoperative risk factors such as preoperative conditions and operative parameters, and can also be prevented by selecting appropriate refractive surgery and using medicine. Non-operative and enhancement surgery can be used to treat refractive regression that has occurred.