眼弓蛔虫病的诊治进展
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国家自然科学基金资助项目(No.81873163)


Progress in diagnosis and treatment of ocular toxocariasis
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National Natural Science Foundation of China(No.81873163)

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    摘要:

    眼弓蛔虫病(OT)是因蛔虫科线虫感染眼组织而引起的一种眼寄生虫病,常由犬弓蛔虫或猫弓蛔虫引起。易感人群多与自己的卫生状况、接触猫犬的频率、食用被弓蛔虫幼卵污染的食物或水源有关。目前在全球范围内的报道多见于儿童,但是近几年也陆续有成人感染的病例被报道,可能因目前对其诊断、治疗和预防还缺乏系统的归纳和总结有关。本文通过查阅国内外相关文献,将OT的四种临床表现、先进的无创诊断技术、实验室免疫学检查进行梳理和补充,同时本文介绍了OT近几年的治疗进展,如驱虫药和激素的联合使用,玻璃体腔内注射与玻璃体手术的应用等。希望引起临床医生对本病的重视,提高OT早期诊断的准确性,保护患者视力。

    Abstract:

    Ocular toxocariasis(OT)is an ocular parasitic disease involving ocular tissue infection by the ascarid-omatidae nematode. OT is usually caused by toxocara canis or toxocara cati. Susceptible population are more likely to be affected by their own hygiene, the frequency of exposure to dogs and cats, and the consumption of food or water contaminated with toxocariasis larvae. Most cases have been reported worldwide in children, but cases in adults have also been reported in recent years, which may be due to the lack of systematic induction and summary of its diagnosis, treatment and prognosis. In this paper, the four clinical manifestations of OT, advanced noninvasive diagnostic techniques, and laboratory immunological tests were sorted out and supplemented by reviewing domestic and international literature. Meanwhile, this paper introduced the treatment progress of OT in recent years, such as the combination of anthelmintic and hormone, and the application of intravitreal injection and vitreous surgery. It is expected that clinicians should pay more attention to this disease, improve the accuracy of early diagnosis of toxocariasis and protect patients' vision.

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孙浩,李姣,郭大东,等.眼弓蛔虫病的诊治进展.国际眼科杂志, 2022,22(4):587-591.

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  • 收稿日期:2021-06-30
  • 最后修改日期:2022-02-25
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  • 在线发布日期: 2022-03-24
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